Sentence examples for knockout embryonic from inspiring English sources

We used gene targeting to produce homozygous Icmt knockout embryonic stem cells (Icmt-/).

We harvested six control and knockout embryonic hearts for real-time PCR analysis.

In the current study, we analyzed Cdc42 knockout embryonic hearts using histology analysis and found that the deletion of Cdc42 resulted in small right ventricles.

The STIM1 antibodies we used did not stain neurons in the sections of the STIM1 knockout embryonic brains obtained from Nieswandt's group.

Moreover, we recently published results showing that palladin knockout embryonic stem cells (ESC) exhibit impaired differentiation into SMC in a embryoid body (EB) SMC differentiation model system [26].

The ubiquitin-conjugating enzymes HR6A and HR6B perform essential functions, as evidenced by the observation that double knockout embryonic stem cells cannot be obtained [ 26].

However, in a third TERT-knockout embryonic stem cell line, 10PTKO-A, chromosome healing was a common event that accounted for 20 of 34 rearrangements.

In contrast, in two TERT-knockout embryonic stem cell lines, chromosome healing accounted for only 1 of 62 rearrangements, with a 23 bp insertion at the site of the sole chromosome-healing event.

DGCR8 function is clearly important, as it is essential for viability in mice and DGCR8-knockout embryonic stem cells show a proliferation defect (Wang et al., 2007).

P130Cas is ubiquitously expressed [10], and the mouse knockout is embryonic lethal with Cas −/− mouse embryonic fibroblasts (MEFs) having disorganized actin stress fibers and defects in cell migration [11].

PDGF-A knockout is embryonic lethal, PDGFRα-null mice die during embryonic development, and mice null for PDGF-C die perinatally [ 34, 40].