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Alternatives to asymmetric synthesis or kinetic resolution include dynamic kinetic resolution, deracemisation and enantioconvergent transformations.
Some earlier efforts have also been carried out for the kinetic resolution of racemic citronellol.
Kinetic resolution of the racemates was carried out by employing lipase B from Candida antarctica (CALB).
Highly efficient asymmetric synthesis of -39 was achieved via dynamic kinetic resolution.
Mandelate racemase (MR) is a promising candidate for the dynamic kinetic resolution of racemates.
Overall, the newly developed nanobiocatalyst has applications towards the kinetic resolution of racemic compounds.
In the present study, the possibility of enzyme catalysed kinetic resolution was investigated.
Applications in chiral synthesis, kinetic resolution, interconversion of enantiomers, and production of oxoacids are all considered.
The present work shows that PREP constitutes a promising biocatalyst formulation for carrying out kinetic resolution with high enantioselectivity.
Enzymatic kinetic resolution is proved as an efficient strategy of accessing chiral secondary alcohols in organic synthesis.
Although kinetic resolution processes could be possible for racemic substrates, these studies might be the matter of future research.
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