Next we asked whether any topological property of the protein interaction network was responsible for the observed variation in the kinetic of pseudocell organization.
Here, in the kinetic-functionality association, we may have uncovered yet another example of nature's modularity design manifestated in the organization of kinetic parameters.
Three-dimensional skeletal muscle tissue has been developed exploiting the influence of mechanical stretch (Vandenburgh & Kaufman, 1979), revealing the pivotal role played by kinetic forces on myofibre organization and muscle maturation.
Kinetic instabilities and self-organization phenomena in chemical and biological systems are reviewed and discussed from the point of view of the unified qualitative theory of non-equilibrium processes.
Such organization may possess several kinetic advantages for the cell [ 10, 11]; for instance, this compact geometry could prevent metabolic intermediates from diffusing away (i.e. substrate channeling), or increase the metabolic flux through the pathway.
Altogether, the findings of such extensive pre-organization of both secondary structures as well as globular proteins suggest that the apparent biological efficiency of protein folding is due in large part to the thermodynamic pre-organization, as opposed to kinetic guidance.
Without the processing of the kinetic laws the network contains 384 reactive organizations generated from the union of 11 elementary organizations.
In formalisms like Systems Biology Markup Language (SBML), however, information about the stoichiometric coefficients required for an analysis of chemical organizations can be hidden in kinetic laws.
In this work, we demonstrated that information hidden in kinetic laws affects the results obtained from chemical organization theory (OT).
First, when this approach is used to extract additional information from the kinetic laws of the reactions, the set of organizations corresponds to the potential steady state and growth states of a reaction network.
