Thus far, in summary, there appear to be two major determinants of the folding patterns of the TA domain peptides of the p53 family: nucleation largely by hydrophobic interactions (a kinetic determinant) and stability induced by ion-pairs or long range electrostatics (thermodynamic determinants).
The aims of this work were trying, primarily, to identify the kinetic-determinant stage of the sorption of Bromacil at a wide range of initial pesticide concentrations (∼5 to ∼500 μg L−1 at pH 7.8), and secondly, to specify the rate constants and other useful design parameters for the application in water treatment.
The differences in kinetic parameters could determine how well fate determinants interact with the plasma membrane (i.e., the association and dissociation rates).
This study provides theoretical evidence that the S0/X0 ratio is the most important determinant of kinetic ability of microorganisms in a batch culture.
Therefore, Q1235 of TL is the primary determinant of kinetic discrimination against c3'dNTP.
The activity of thioredoxin reductase is therefore a crucial determinant of the kinetic profile of thioredoxin oxidation reactions.
The structure/energetics of the TS for the rate limiting step of irreversible denaturation of WT and PH1 mutants is strikingly similar, suggesting a fine-tuning of the structure/energetics of this TS as determinant for the kinetic stability of PH1 mutants (unpublished observations).
We determined the kinetic parameters of wild-type and mutant mAOX1 using different aldehyde and purine substrates, gaining insights into the molecular determinants guiding substrate specificity in XOR and AOX1.
As mentioned above, in lamellar growth of single crystal, different prism fronts are in competition with each other, and those that have lower rate could form the determinant faces because from a kinetic point of view, lower rate is a controlling factor.
Second, the appreciation of rise or fall of cTn levels during a 3- or 6-hour kinetic, though still debated, seems to be determinant to rule in AMI [ 11, 12].
