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Which kind of DNA damages is refractory to DNA repair and triggers a permanent cell cycle arrest was not clear until recently.
In eukaryotic cells, DSB repair by HR requires the presence of an undamaged, homologous DNA molecule and, because this molecule is invariably the sister chromatid, this kind of DNA repair pathway is restricted to the S and G2 cell cycle phases.
Furthermore, the DNA nanomachine could be used for nucleic acid, thrombin and adenosine highly sensitive specific detection based on isothermal, and homogeneous hairpin DNA cascade signal amplification in both buffer and a complicated biomatrix, and this kind of DNA nanomachine could be efficiently applied in the field of biomedical analysis.
Almost a kind of DNA.
David Lodge regards his fiction as "a kind of DNA of the imagination".
But a new kind of DNA decoding machine happens to use such fragments as its starting material.
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It's atmospheric and intriguing, though not the kind of DNA-reconfiguring performance last year led us to expect.
A proof of direct regulation would require a promoter analysis or some kind of DNA-protein binding experiment or in silico analysis.
We are now routinely utilizing this method to detect ancient DNA and believe that it will be applicable for detecting other kinds of DNA from archaeological samples, as well as other kinds of samples with trace amounts of DNA.
But he says new kinds of DNA profiling will be tried in the coming months.
Currently, two kinds of DNA are subject to forensic testing: nuclear DNA and mitochondrial DNA (mtDNA), which is passed from mother to child.
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