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To test whether other factors can modulate NK cell killing activity and subsequently killing frequency, we stimulated freshly isolated human NK cells with IL-2, IL-15, IFN-α or polyI∶C for 7 days and assessed their killing activity.
Rituximab treatment enhances the killing frequency of fresh and IL-2 activated NK cells.
The 51Cr release data can only give an average killing frequency as the activity of many NK cells is assayed.
IL-2 and IL-15 are equally effective in enhancing the killing frequency of resting NK cells.
Significantly, Rituximab, a therapeutic monoclonal antibody increases the killing frequency of both resting and IL-2 activated NK cells.
Moreover, these reports do not give any idea about the killing frequency of a single NK cell.
Similar(43)
Understanding whether killing frequency- or number-dependent is critical for prediction of the efficacy of T-cell based vaccines, in part, because the number and the frequency of memory T cells are affected differently following infections with heterologous viruses [49], [50].
Well now you can thanks to the genius behind phonejammer.com, a north London company that manufactures these beauties, which are capable of killing mobile frequencies within a radius of up to 30 metres or so, depending on the size and power of the jammer.
For years, various British governments have been floating the idea of killing the FM frequency altogether, with Culture Minister Ed Vaizey saying earlier this year that the UK is reaching a "tipping point" in the conversion to digital radio.
Nevertheless, only little information exists about killing potential or frequency of NK cells.
He talked with increasing frequency of killing himself, and made at least one attempt.
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