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The findings suggest that the antioxidant selenoprotein TrxR1 under some circumstances can be converted into a potent prooxidant killer of cells.
Those findings in combination with the intracellular ROS production triggered by SecTRAPs, as shown by DCF fluorescence and the protection from cell death by antioxidants, collectively show that the selenoprotein TrxR1, a key player in antioxidant defense, can be converted into a potent prooxidant killer of cells when its highly reactive Sec residue becomes compromised.
Thus, autophagy is a double-edged sword that can work both as a protector and a killer of cells.
Thus, the function of autophagy has been described as a double-edged sword that can work both as a protector and killer of cells, which depends on the developmental stage of the disease or the surrounding microenvironment.
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SecTRAPs are prooxidant killers of cells, triggering mechanisms beyond those of a mere loss of thioredoxin reductase activity.
Thus, the GCV HSVtk combination can be used as a multifunctional inducer or killer of senescent cells.
More importantly, PMVDS stimulated both cytotoxic T cells and natural killer cells of cell-mediated immunity to provide tumor (B16-ova-Melanoma) protection in around 40% of vaccinated mice and significantly delayed tumor progression in rest of the mice.
Methods have been developed to convert a patient's cytotoxic T cells into efficient and specific killers of cancer cells in patients with leukemia.
Chemotherapy and radiation are efficient killers of tumor cells.
The other major killer of the endothelial cells in the lining of your heart is chronically high levels of endotoxin LPS.
Percentages of natural killer (NK) cells and of apoptosis of CD4 lymphocytes upon diagnosis are presented in Table 1.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com