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A low level of pro-apoptotic Bad or a high level of pro-survival Bcl-xL implies gate AND, which allows for the initiation of apoptosis only when two stress stimuli are simultaneously present: the rise of the p53 killer level and dephosphorylation of kinase Akt.
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The Xoom was hyped to iPad-killer levels.
In spite of the golden presence of Brad Pitt as the killer, a level-headed professional named Jackie Cogan, the movie has an agreeably scuzzy, small-time feeling.
If the prospect of spending a thousand days up to 140 million miles away from the Earth was not enough of a deterrent, killer radiation levels and enforced radio silence would surely deter most volunteers from travelling to Mars.
The first-act finale, "Hakuna Matata," and the swoony anthem, "Can You Feel the Love Tonight?" have distinctive melodies -- or melodic phrases -- but neither rises to the killer-diller level you'd expect from a number that brings down a curtain at intermission or brings down the house at 11 o'clock.
"And now we can offer killer service-level agreements with no excuses and no whining," Salerno says.
Our first stop was Luxor because I remembered they had a killer multi-level arcade called Games of the Gods with walls airbrushed with images of King Tut and ankh patterned carpet.
On its most primal level "Killer on the Road" recounts the crime sprees of men like Charles Starkweather.
It's all the Woo flourishes...that elevates The Killer to another level".
European harbour seals have problems in reproductive and immune functions associated with high levels of PCBs and related contaminants, and a survey off the Washington coast found PCB levels in killer whales were higher than levels that had caused health problems in harbour seals.
To determine the involvement of GzmB in apoptotic cell-in-cell death of immune killer cells, GzmB levels were first analyzed in a panel of immune cells investigated.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com