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Ligands for the activating receptor NKG2D (natural killer group 2 member D) are such key danger signals that are presented by "stressed" cells.
In addition to a shorter life span, NK cell expansion is tightly controlled by constitutively expressed inhibitory receptors, such as killer immunoglobulin-like receptor (KIR), CD94/ natural killer group 2A (NKG2and and other inhibitory receptors (Long, 2008).
Specifically, if the signaling of an activating receptor, such as CD16 or natural killer group 2, member D (NKG2D), dominates, NK cells will kill target cells without prior sensitization, which provide the rapid, first-line defense mechanism.
At the same time, it attenuates natural killer group 2, member D (NKG2D) expression.
MICA is a natural ligand for the activating receptor natural killer group 2, member D (NKG2D) expressed on the surface of natural killer (NK) cells.
Furthermore, the relationship of serum sMICA levels and natural killer group 2, member D (NKG2D) expression on natural killer (NK) cells was also evaluated.
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Using improved radar, these ships formed "hunter killer" groups to go after the German wolf packs.
While Young was moving on the solo front, Stills, nurturing a passle of killer group-oriented songs, pursued his fraught relationship with singing sensation Judy Collins and looked to form a new band.
"The consequence is that you will have a couple of groups getting drawn … that are Groups of Death, that will be killer groups; there's not even one easy team or whatever," said Klinsmann, whose team won a record 16 games in 2013, won the CONCACAF Gold Cup and finished first in the CONCACAF World Cup qualifying tournament.
Natural-killer group 2, member D. Peripheral blood mononuclear cells.
Fig. 3 Representative histogram of natural-killer group 2, member D (NKG2D) expression on lymphocytes before and after stimulation.
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