Although there is savage humour in Ui's satanic wooing of Betty Dullfoot, whose husband he has just killed, Goodman gradually wipes the smile from our faces.
Exogenous insulin (s.c. pellets or islet-transplantation) restored normoglycemia in every mouse, whereas depleting CD8+ T cells transiently halted direct CTL-mediated β-cell killing so gradually restored normoglycemia in the majority of diabetic mice (responders), with remissions typically lasting for more than one week.
Deriving strength from their large, poorly nourished numbers, the farmers gradually killed off most of the hunter-gatherers and drove the rest from their land.
In 1579, however, the fair came under the supervision of the imperial censorship commission (Frankfurt being a free imperial city), and this action gradually killed it.
WHEN, 65m years ago, an asteroid that fell near the Yucatan peninsula wiped out the world's dinosaurs, it did not exterminate them all at once, but triggered changes to the atmosphere that gradually killed off the survivors.
Starting in the lower reaches, moving ever further upstream as industry and urbanisation spread south, the river was gradually killed: the last trout was caught, close to the source, in 1934.
Japan's entrance into the war cut off Lyon's already restricted supply of Japanese cocoons, which, because they were cheaper than the French ones, had, since the beginning of this century, gradually killed off the silkworms and even the mulberry trees around Vaison and other towns.
As the drought in the Horn of Africa gradually killed everything Farhan Abdi Ali had worked for, all his life savings, he separated his animals into two groups: Those that produced offspring that could be sold, and those that produced milk.
Metastatic tumour explants cultured with MEDI-565, but not Cont BiTE, were surrounded by T cells, detached from the bottom of the well, and were gradually killed (Supplementary Figure 1).
Neuro-2a cells (H2Ka) were gradually killed at decreasing target/effector ratios and were comparable to lysis of A20 (H2Kd, Figure 1B), with significant difference only at the lowest target/effector ratio (P<0.05).
