The goal was to have an approved anthrax drug that could kill strains of the bacteria that were resistant to the older antibiotics.
Pyocin S3 was shown to use the type II FpvA receptor, while pyocin S2 was found to kill strains harbouring the type I FpvA receptor [106]–[106].
A new nanosilver-based gel known as SilvrSTAT™, for example—introduced in fall 2012 as a wound-care antimicrobial by Utah-based ABL Medical was proven in laboratory tests to kill strains of methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant enterococci (VRE) within minutes, says ABL Medical managing director Keith Moeller.
This antibody-mediated killing was dose-dependent, as 1% and 0.1% O1-specific serum did not kill strain RB50.
That kills strains of the virus susceptible to nevirapine, leaving resistant strains to survive and multiply.
Lugdunin also killed strains of Enterococcus, a bacteria that can cause inflammation of the heart, urinary tract infections and bloodstream infections, that are resistant to the antibiotic vancomycin.. What's more, when applied to mice, the new antibiotic was found to clear or reduce skin infections of S.aureus.
Acnevac or autovaccines containing killed strains of P. acnes and/or Staphylococci have been tested in acne and normal healthy subjects [25].
In this model system, lethality is a rather clear-cut parameter and, based on the number of mice killed, strains are classified as non-killer (<2 of 10 mice killed), killer (>8 mice killed) [49] or intermediate.
In vitro studies have shown that 50,000 90,000 IU/ml of vitamin D3 inhibited growth or killed strains of Staphylococcus aureus, Streptococcus pyogenes, Klebsiella pneumoniae, and Escherichia coli.
Aside from the deputy, Godbolt was related to or acquainted with the seven people he killed, Strain said.
In this regard, Spiroplasma strains associated with several species of Drosophila, including a non-male killing strain of D. hydei, are known to possess bacteriophages with lytic activity [22], [38], [39].
