Measuring CTL killing rates with this in vivo assay requires not only modeling killing itself but also the flow of targets into the spleen.
Kill rate, prey selection, interaction with prey and scavengers.
Tumor size was represented as a competition of tumor growth and kill rates, but with drug effect incorporated into the tumor kill rate.
After induction of 1.0 μg/ml Dox, the killing rate of rAAV+Dox+GCV with 104 vp/cell to MCF-7 reached 36%, as detected by using the MTT assay in the presence of GCV (3.0 μg/ml).
Therefore, the equation of cell killing rate in (15), although coming with much less fluctuation, is an increasing function of tumor volumes, and does not affect much on the clinical outcomes.
Parameter r pmk represents phagocytosis (killing) rate of Kupffer Cells when Kupffer Cells begin to kill pathogens.
If we assume that as a result of epitope decay the GP effector killing rate kGP falls exponentially with time as kGP = k0exp(−μt), we estimate k0 = 4.05 (3.02, 5.76) and μ = 7.72 (6.16, 9.36 ×10−3 min−1 for killing by GP-specific effector CTL.
We adjust the pH of the static Ag/Mg to 8 by adding NaOH (Note that Mg will not react with NaOH) and study the bacteria killing rate.
We want to estimate the cell killing rates per fraction.
Comparing the two groups (with RT and without RT) of IBTR data only gives us the total cell killing rates on the completed RT.
