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We believe the 95% inhibition figure to be important, as this is the level of tumour cell kill required for most logarithmic kill models to show effects (Goldie and Coldman, 1979).
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To map QTL affecting virulence, we measured the ability of each progeny strain to kill model hosts, larvae of the wax moth Galleria mellonella.
An adaptation of Skipper's log cell kill model of tumour response to chemotherapy was applied to serial tumour measurements of 46 locally advanced primary breast carcinomas undergoing neoadjuvant chemotherapy.
In this paper, three mathematical cell-kill models including log-kill hypothesis, Norton Simon hypothesis and Emax hypothesis are considered.
Pakistani police say the brother of killed model Qandeel Baloch has confessed to strangling her to death for "family honour" because she posted "shameful" pictures on Facebook.
The South African athlete, who is accused of killing model Reeva Steenkamp on Valentine's Day, was granted one million rand (£73,000) bail, and released from police custody a fortnight ago.
I followed Avanzino at the San Francisco SPCA and when I was confident that the no-kill model Avanzino had started and I had continued was sustainable, I decided to leave San Francisco so that I could take its no-kill model national, starting with New York City.
We discuss extensions to the basic CTL killing model to explain this discrepancy and propose experimental tests to distinguish between them.
In the nematode killing model, E. faecalis and S. mitis strains presented a similar virulence (LT50NSTRMIT 5.4 days vs LT50NEF26 4.6 days; (p: not significant)) (Fig. 1A).
The dose escalation concept was based on the Skipper Schabel Wilcox model, also termed the log-kill model – the first significant proliferation model in clinical oncology [ 8].
As noted by the reviewer, a similar stochastic cell killing model was described in Spencer et al, Nature, 2009 with respect to TRAIL-induced apoptosis.
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