Sentence examples for key underlying mechanism from inspiring English sources
Downstream targets of B-Raf such as ERK [24], the immediate early gene Egr1 [26] and CREB [22], [27], [28] are all activated and are necessary for the consolidation of recognition memory, suggesting this signaling pathway is a key underlying mechanism necessary for consolidation of long-term memory.
The key underlying mechanism is supposed to be the presence of chronic inflammation [ 6].
Interestingly, the concerted action of ABT-737 and TRAIL to trigger the accumulation of truncated Bid (tBid) at mitochondrial membranes is identified as a key underlying mechanism.
It is probably the case that inflammation is the key underlying mechanism while renal dysfunction accelerates the process [ 9, 23, 24].
In addition, chronic inflammation in adipose tissue has been considered as a key underlying mechanism for the development of obesity-related metabolic syndrome [ 17].
According to the changes in the bonding and the volume relaxation related to the carbon defects in SiC, an increase in the population of antisite CSi was likely the key underlying mechanism of the irradiation-induced shrinkage of the HNLS fibers.
Pinpointing key problem contexts (hotspots), opportunity structures and precipitating conditions provides an opportunity to respond at a local neighbourhood or organisational level and target key underlying mechanisms, positioning prevention and intervention resources and efforts where they are most needed.
For each disease, it will be important to dissect the key underlying mechanisms.
The objective of this work was to establish a multiscale, mechanistic model that can capture the key underlying mechanisms for immunogenicity against antigenic therapeutic proteins.
It is an independent risk factor for death in these patients, and one of the key underlying mechanisms for this could be an increased risk for malignant ventricular arrhythmias.
The temporal variation in miRNA expression levels at diagnosis and relapse suggested that miRNAs control the expression of key proteins underlying mechanisms leading to leukemogenesis and relapse.
