Sentence examples for key to activation from inspiring English sources

The key to activation of Eσ by DctD250 in diverse bacteria is the ability of the activator to make the appropriate interactions with σ in the context of the Eσ-promoter closed complex; thus, comparison of interacting regions of σ and bEBPs between S. Typhimurium and phylogenetically diverse bacteria is a good predictor of success.

When the crew emerge from slipace, they soon discover another Halo installation; realizing the danger the ring presents, Keyes sends the Master Chief to kill Regret while she and Johnson find Halo's key to activation, the Index.

Collectively, these results indicate that increased expression of CYT-C is key to activation of apoptotic effectors CASP3, CASP6 and CASP7 to be able to induce cell death.

These experiments suggest that, in addition to the occupancy of the kinase nucleotide-binding pocket, the ER stress-induced conformational change of the cytosolic portion of IRE1 containing both kinase and RNase domains holds a key to activation of I642G I642G

Key to the activation of this killing mechanism is the reaction of reactive oxygen species with intracellular iron from damaged iron-sulfur clusters, resulting in the formation of hydroxyl radicals via the Fenton reaction, which leads to subsequent cell death.

The interferon regulatory factor (IRF) genes are also key to the activation of the IFN pathway [ 53].

Notably, threonine phosphorylation within the C-NOI is key to the activation of ETI by RPM1 [ 14, 15].

It is evident that the PI3K/AKT pathway is key to EBV activation in both cell-free and cell-to-cell contact infections.

Src-homology 2 domain-containing phosphatase 2 (SHP2) appeared to be key to SK1 activation, and may function as an adaptor protein between SFKs and LEPR.

The extracellular N-terminal regions of chemokine receptors are key to their activation: chemokines first bind to the N-termini and induce a conformational change thereby interacting with the transmembrane domains to activate the receptor.

We have recently shown that Ca2+ signaling is a key to EPC activation [ 9– 11, 31, 32], so that they are suitable to serve as positive control for many substances commonly utilized to study subcellular Ca2+ movements [ 3, 25].