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Pro-British Unionists' complaints that the I.R.A. was reneging on its promise to dispose of its arsenal have been a key stumbling block in Northern Ireland's peace effort.
But repealing the individual mandate was a critical strategic victory for conservative health reformers, because the mandate was a key stumbling block in last year's failed effort to repeal and replace Obamacare.
In March 2012 the Taliban said it had suspended preliminary negotiations with Washington, citing US efforts to involve the Afghan government as a key stumbling block.
They learned about the transplant-rejection response, which would become the key stumbling block to successful heart transplants.
The key stumbling block for Japan was the demand by the European Union and Latin American countries that its Antarctic whaling program end within a set time frame.
But he said he would not support halting Iran's uranium enrichment, which is a key stumbling block for talks between Iran and world powers.
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U.S. proposals on automobile content, government procurement, intellectual property, investor dispute settlement and treaty expiration — dubbed "poison pills" — remain key stumbling blocks.
Key stumbling blocks include the return of property to tens of thousands of Cypriots who fled their homes in 1974, and the question of whether any Turkish troops will remain in northern Cyprus after reunification.
Medicare served as one of the key stumbling blocks during the 2011 budget negotiations.
A pessimist may see demographic growth (and its effect on per capita growth), automation and limited natural resources as key stumbling blocks for a return to sustained growth.
While the key stumbling blocks for a strong outcome in Cancun, Mexico weren't resolved, there were constructive movements on a number of the key elements of international efforts.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com