The AT1R-ZD7155 complex structure revealed key structural features of AT1R and critical interactions for ZD7155 binding.
This diversity in ligand structure was intended to enable key structural features of the ligand, required for efficient protein binding, to be determined.
Structure-function studies have identified that key structural features on these phenolic-glycosides are crucial for potent activity.
X-ray crystal structure analysis confirms that [NiFe('S2Se2')(CO)3] mimics the key structural features of the enzyme active site, including a doubly bridged heterobimetallic nickel and iron center with a selenolate terminally coordinated to the nickel center.
The molecular electronic structures and electron densities around these functional groups are the key structural features that determine the effectiveness of inhibition[10, 11, 12].
The TMACC interpretation of the DHFR data set identified many key structural features for DHFR inhibition.
Key structural features dictate how the HIV envelope protein functions and interacts with the human immune system.
However, the folding kinetics is likely to depend more on a few key structural features.
The key structural features responsible for the inhibition activities were discussed in detail.
Griffin does not share Gewirth's goal of providing a logically inescapable argument for human rights, but his overall view shares key structural features with Gewirth's.
All of the protein kinases have a similar bilobal fold, and their key structural features have been well studied.
