Sentence examples for key steps required from inspiring English sources

The transport of glucose through the cell membrane via glucose transporter proteins and its subsequent intracellular phosphorylation by hexokinases are key steps required for its cellular accumulation [28].

Indeed, integrins perform key roles at several key steps required for cell migration: adhesion assembly, disassembly, and turnover [ 29, 30].

It is recognized that the precise carcinogenic mechanism(s) is unknown for essentially all chemicals, and the MOA concept attempts to address this knowledge deficit by focusing on key steps required (i.e., necessary) for the carcinogenic process.

Then we read and analyzed the full text of the selected resources to determine key steps required to implement a successful transition to country ownership and to identify potential determinants of readiness for transition.

At first entry the Citizen Scientist is provided with a brief web based training tutorial in which the task and key steps required to score each image are described.

The Hwang team's papers, published in 2004 and 2005, posited spectacular achievements in stem cell biology; the second paper described the first-ever human embryonic stem cell lines that were genetically matched to patients, a key step required before embryonic stem cells can be used in medical treatment.

Furthermore, XRCC3 over-expression resulted in a significant increase in the expression of the human trefoil protein TFF1 a modulator of cell motility, another key step required for cell invasion and metastasis.

Proteolytic action on the ECM is a key step required for the initiation of tumour invasion and angiogenesis.

A key step required before degradation of IκB-α is IKK-2-dependent phosphorylation of the N-terminal residues Ser32 and Ser36.

Taken together, the results we present establish that Okazaki fragment ligation is a key step required to enable effective and timely PCNA unloading by Elg1-RLC during DNA replication.

So a key step requires that two village elders or guarantors sign letters testifying to the recruit's "identity and motivation to serve".