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Leptin is a key starvation factor.
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1 A key risk factor for the syndrome is starvation with early published reports being prisoners of war. 2 In recent times, refeeding syndrome has been confirmed in hunger strikers, individuals with anorexia nervosa and chronic alcoholics.
Similarly, ppa (soluble inorganic pyrophosphatase), a key Pi starvation induced gene [ 45], was down-regulated.
It has recently been shown that both SPX1 and SPX2 can inhibit phosphate starvation responses through Pi-dependant direct interaction with PHR2, a key transcription factor controlling the majority of Pi-responsive genes.
Another possible factor is CEBPB/C/EBPβ, [CCAAT/enhancer binding protein (C/EBP), β], which is one of the key transcription factors responsible for starvation,, and is also implicated in circadian regulation of autophagy.
Starvation is also considered a key factor for inducing the germ tube tip to differentiate into an appressorium [ 28].
Economic conditions are often the key deciding factor in elections.
Several interviewees mention unemployment as a key underlying factor.
Charges are also a key differentiating factor.
More importantly, it appears that the ability to mobilize triglyceride was the key factor in protecting cells from starvation-induced cell death.
Deployment of a stochastic model with awareness of steric interactions between ribosomes (queuing effects) revealed that changes in histidine codon translation rate, rather than alterations in ternary complex acquisition, was the key factor governing increases in ribosome loading on the GCN4 ORF under amino acid starvation conditions.
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