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The key restraints used for protein structure determinations are nuclear Overhauser enhancements (NOEs) between protons, where the intensity of the observed NOE is approximately proportional to r−6 (r is the distance between the two interacting protons).
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Thus, the cross-link between PP2Ac Lys28 and IGBP1 Lys158 afforded a key restraint about the complex structure, and owing to the sparsity of the inter-molecular cross-links, this cross-link is not redundantly provided by other cross-links.
Facilitation of cGMP-dependent signalling by combination therapy, therefore, exerts a key restraint on one of the central processes leading to overt pulmonary fibrosis, that of extracellular matrix deposition.
The key is restraint – a baby pinch of very fine sparkle on the inner eye, or a gentle dusting of the lids.
In my view, the key to restraint is not eating less than you want, but eating foods that get you to satisfaction on fewer calories.
This is owing to the presence of shear keys which restraint deformations in the transverse direction.
It "deserves the same respect as the rest of the world," he says.Even so, says Mr McLarty, "the key word is restraint: we will judge case-by-case".
In Mr Bush's first five years real per head federal spending grew by 3.1% annually, making him the most fritter-happy president since Lyndon Johnson.Mr Bush, though, is not the only president who has run up the bill when governing with friends.William Niskanen, a former economic adviser to Ronald Reagan, speculates that divided government itself may be the key to fiscal restraint.
Restraint is key, he said, because a doctor could apply Zeltiq to "the same spot" in the same day, which isn't how it's meant to be used.
That restraint is key.
Diplomacy, interdependence, respect and self-restraint are key elements for a constructive solution of the almost six decades conflict between them.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com