Sentence examples for key pathological changes from inspiring English sources

Using the rat ACLT model of PTOA, several of the key pathological changes to cartilage and synovium has been well documented (Caron et al. 1996; Elsaid et al. 2012; Jay et al. 2012; Elsaid et al. 2015).

One of the key pathological changes that occurs acutely following brain injury is disruption of the blood-brain barrier (BBB).

Fig. 2 shows representative 3D volume reconstructions (left panels) with corresponding mid-lung coronal µCT sections (middle panels) and magnification of key pathological changes (right panels) for lungs at day 28.

Our results demonstrated that PDGF-BB significantly induced ASMCs proliferation and migration, which was one of the key pathological changes of airway remodeling in asthma, and our discovery was the same as results of former studies [ 30, 31].

Although each model can reproduce components of the key pathological changes that occur in ALI, none is capable of fully recapitulating the classical triad of features observed in patients: severe neutrophilic alveolitis with deposition of hyaline membranes and the formation of microthrombi.

Apoptosis of cardiomyocytes is considered as a key pathological change in DCM [ 5].

β-Catenin was induced by HNE and HOG-LDL, and blocked by NAC treatment in endothelial cells Dysfunction of endothelial cells is a key pathological change in the development of retinal diseases, especially in diabetic retinopathy [ 7].

Thus, although there is variation in the overall distribution and type of cellular neuropathology underlying PDD, pathological changes at key cognitive nodes display a relative consistency, and support the neural network model of PDD.

We assessed if there were any significant pathological changes to the key haematological and biochemical markers from baseline to the 15th day of follow-up as well as the determinants of such changes.

Representative micrographs (Fig. 2) illustrate areas with pathological changes (see Figure Legend for key to labeling).

New treatments have complemented advances in under-standing of pathological changes in SpA, especially the key role played by enthesitis in peripheral and spinal lesions.