Sentence examples for key nucleotide from inspiring English sources

Orotate is then converted into the key nucleotide uridine-5′-monophosphate (UMP) by UMP synthase and then phosphorylated to UDP.

Flux through each branch of the PPP can provide ribose-5-phosphate and then 5-phosphoribosylpyrophosphate, a key nucleotide precursor.

The effect of mutating G150, U151, and A152 was moderate but the effect of the A153G mutant was dramatic pointing to this nucleotide as a key nucleotide for reactivity.

A molecular modeling study demonstrated that EGCG exerts its inhibitory effect on DNMT1 function by blocking entry of the key nucleotide cytosine into its active site by hydrogen bonds and, thus, prevents DNA methylation (Fang et al. 2003).

Eukaryotic tRNAGln and tRNAGlu recognition determinants are found in equivalent positions and are mutually exclusive to a significant degree, with key nucleotides located adjacent to portions of the protein structure that differentiated during the evolution of archaeal nondiscriminating GluRS to GlnRS.

SHAPE reactivity changes at key nucleotides in Region1 and Region2 were compared between different constructs and the 354-nt RRE.

We also identify the consensus DNA-binding motif found in all the GlnR binding sites and determine key nucleotides in the motif for specific GlnR binding.

The first guide sequence (from the 5′-terminus) was directed to G1702 in 18S rRNA, which was one of the key nucleotides of the ribosome-decoding center [ 25].

Within a highly functional sequence, there are key nucleotides whose mutations provoke a significant disruption of the structure, whereas the majority of nucleotides have a more reduced impact on it.

To identify key nucleotides required for GlnR binding, complementary oligonucleotides were designed to mutate or alter the distance of key residues and annealed to generate DNA fragments for EMSAs (Additional file 9: Table S4).

The α subunit of eIF2 structurally mimics E site tRNA, and the loop of its N-terminal domain eIF2α-D1 makes contacts with key nucleotides at the −2 and −3 positions of the mRNA.