Sentence examples for key mutations from inspiring English sources

Now, "we find key mutations in genes that are expected to be mutated, but then we find many other mutations," which need to be tested in avatars to determine whether they might be clinically relevant.

The five key mutations could not be reversed first, because the receptor would be rendered useless.

So he and his colleagues reversed these key mutations to their old form.

Identifying these key mutations is where the transgenic mice come in.

Moreover, whole-genome sequencing typically contains mistakes, so key mutations might be missed.

These were then grown in culture (pictured) and sequenced to reveal key mutations in certain cancer genes.

In the first, the receptor acquired the seven key mutations that made it sensitive to cortisol and not to other hormones.

Key mutations that helped drive the pathogenicity of the 1918 Spanish Flu rely on host chaperones for their fitness.

Mechanisms of resistance to several classes of antimalarial drugs have been linked to key mutations in the Plasmodium falciparum genes.

The assay qualitatively reproduces the effects of complexin-1 and key mutations on both spontaneous release and evoked release that have been observed in cortical neuronal cultures.

This paper reviews the key mutations and mechanisms associated with resistance to the nucleos(t)ide analogues approved for clinical use and discuss new targets for drug development.