Sentence examples for key molecular features from inspiring English sources

These inhibitors were derived via systematically deconstructing a literature inhibitor to understand the basic pharmacophore and key molecular features required to inhibit the protein receptor.

I will discuss some of the key molecular features that distinguish the hepatocyte polarity phenotype from that of monopolar, columnar epithelia.

CIMP-high is independently associated with clinical and key molecular features in colorectal cancer.

Our analyses of differentially expressed P. temperata genes reveal key molecular features reshaped by bacteria in mutualism with the nematode partner.

The x-ray crystal structures of the TTR inhibitor complexes presented here illustrates the key molecular features for inhibitor binding and provide the structural basis for the stabilization of the native tetrameric TTR.

In particular, key molecular features related to biomass recalcitrance, specifically cellulose ultrastructure and accessibility were, studied.

Mitochondrial DNA (mtDNA) rearrangements are a key molecular feature of this disease, which manifest a broad phenotypic spectrum.

Here we show, using an isogenic human embryonic stem cell model of RTT, that MECP2 mutant neurons display key molecular and cellular features of this disorder.

In 1997 Lipinski published a key paper identifying molecular features that appear to be found in orally available drugs [11] the Lipinski "rule of five" has since become the yardstick by which potential development compounds are judged.

These include avian species, which share key molecular and cellular features of epiblast morphogenesis with the mammals (Sheng, 2014), yet are evolutionarily distant enough to serve as an outgroup.

Key molecular and histochemical features underlying age-dependent phenotypic alterations of the human skin include decreased collagen production in dermal fibroblasts, leading to the fragmentation and disarray of collagen fibrils in the dermis.