Sentence examples for key mediators involved from inspiring English sources

IL-1 and TNF-α are key mediators involved in the initiation of the inflammatory response.

Normal urinary bladder function requires bidirectional molecular communication between urothelium, detrusor smooth muscle and sensory neurons and one of the key mediators involved in this intercellular signaling is ATP.

Hormones are another family of key mediators involved in APR.

Here we show that CCL-1 is one of the key mediators involved in the development of neuropathic pain.

Agents blocking key mediators involved in T-cell exhaustion are already available and FDA approved for treating several types of solid tumors.

An improved understanding of the mechanism of sepsis, and the ability to identify and quantify key mediators involved in its pathophysiology, offers the prospect of reliable diagnostic and prognostic tools.

These results support that Egr-1 is a key mediator involved in PDGF-induced Rad expression in RASMCs.

23 Thus, these findings suggest that CCND1, located at 11q13.3, may be a key mediator involved in the genesis of MRT.

Together these studies suggest that TLR2 is a key mediator involved in promoting cell migrational, invasive and destructive mechanisms in the RA joint.

TNF α is known as one of the essential cytokines in promoting muscular inflammation at cellular level [ 55, 56]; it has been recently confirmed to be a key mediator involved in IM pathogenesis and, consequently, emerges as a potential therapeutic target [ 57– 57].

In particular, the use of a fully defined medium (FDM) would avoid biases induced by unidentified factors contained in serum, and would also allow key molecular mediators involved in such a process to be identified.