Sentence examples for key locus for from inspiring English sources

The hub locus/allele may be a key locus for identifying QTLs networks in which each component contributes directly to the final phenotype.

Indeed, 11β-HSD1 (mRNandnd enzyme activity) is expressed in the hypothalamic arcuate nucleus, a key locus for appetite control [180].

Older individuals who exhibit learning and memory impairments have elevated glucocorticoid levels that parallel both cognitive deficits and shrinkage of the hippocampus, a key locus for memory formation.

Lower expression is found in most cells of the CNS and spinal cord and includes notably the paraventricular nucleus of the hypothalamus, a key locus for glucocorticoid feedback control of the HPA axis [180].

Elevated glucocorticoid levels have widespread effects within the central nervous system, including deleterious effects on the structure and function of the hippocampus, a key locus for cognitive function, which also highly expresses glucocorticoid receptors (7, 8).

Another example that might enlighten the evolution of bacterial pathogenicity is the plasticity zone (PZ) of Y. enterocolitica, a 199 kb key locus for high pathogenicity that includes YAPIYe, secretion systems, hydrogenase loci essential for gut colonization of S. typhimurium and H. pylori [ 122], and iron acquisition systems.

It has been confirmed that Ser966, Asp960 and Asp1086 are key loci for esterase activity (Atkins and Glynn, 2000).

The need for developmental transitions to be timed accurately and robustly is reflected in the emerging complex, multi-layered epigenetic regulation of some key loci, for example the flowering control gene Flowering Locus C (FLC) (Simpson and Dean, 2002; Csorba et al., 2014).

The Agrobacterium genome encompasses more than a hundred of PBPs, of which some of them were already described as key-loci for species identification.

Therefore, Mll1 seems to be required to mediate the transition from a silenced to an active transcriptional state in key loci of postnatal neural precursors necessary for the induction of neurogenesis [ 46].

Therefore, we hypothesized that pseudomonads and cyanide may inhibit biofilm formation through limiting the induction of one (or both) of two key loci required for biofilm formation, the epsA-O and yqxM-sipW-tasA operons [40] [45].