Sentence examples for key initial step from inspiring English sources

"Raising the affordable housing low- and moderate-income goal to 50 percent was the key initial step in setting Fannie and Freddie on a path to insolvency," said Peter J. Wallison, a conservative scholar who sits on the Congressionally appointed Financial Crisis Inquiry Commission, which was created in 2009.

A key initial step was determining how much virus is needed to infect an unvaccinated animal.

Substrate preparation is a key initial step in the production of quality thermal sprayed coatings.

Although the performance in these diverse applications is governed by a complex interplay between the nanomaterial, the properties of included drugs (if any), and the biological system, nanoparticle-membrane interactions constitute a key initial step and play a key role for the subsequent biological response.

Priming T cell generation is a key initial step in T cell-based immune responses against tumor cells and pathogens [18], [25].

The blood brain barrier (BBB) is rich in type IV collagen, a substrate of MMP-9 (gelatinase B), and its breakdown is a key initial step in the pathophysiology of CNS leukocyte influx [8], [9].

Local invasion by and dissemination of cancer cells from a primary tumor are key initial steps of metastasis, the most lethal aspect of cancer.

According to recent research on slum upgrading in Brazil, two key initial steps are important for the intervention's success: defining where to conduct the interventions, and then mapping the areas of intervention.

Acyl-CoA synthetases (ACSs) are the key enzymes responsible for this fundamental initial step in lipid metabolism.

Analysis of esterases involved in the key initial metabolic steps of the BBP degradation pathway indicated the presence of multiple esterases in both species.

No EGTs were assigned to acetate kinase and phosphotransacetylase, which are key enzymes in the initial step of acetoclastic methanogenesis in Methanosarcina [ 45].