Sentence examples for key for the functional from inspiring English sources

A large quantity of data now supports the notion that short linear motifs (SLiMs), which are protein interaction modules enriched within intrinsically disordered regions, are key for the functional diversification of these isoforms.

We conclude that palmitoylation is key for the functional cooperation of SP-C with SP-B that enables cholesterol-containing surfactant films to reach very low tensions under compression, which could be particularly important in the design of clinical surfactants destined to replacement therapies in pathologies such as acute respiratory distress syndrome.

The development of more model invasive species amenable to reverse genetics will be key for dissecting the functional role of candidate loci and will be a step forward for invasion genomics (Stewart et al. 2009).

The transcript database contained full-length mRNAs encoding most alkaloid biosynthetic enzymes, which is a key requirement for the functional characterization of novel gene candidates.

Consequently, metabolomics science the quantitative measurement of metabolism in conjunction with metabolic modelling is a key discipline for the functional interpretation of whole genomes and especially for testing the numerical predictions of metabolism based on genome-scale metabolic network models.

Therefore, the PC-GSEA extracted meaningful contrasts of the biological functions and the phenotypes to interpret the PC1.> Since the PC scores representing the functions and phenotypes were calculated by linear combination of the expression profile and the loading coefficients, genes with large loading coefficients on each PC would be the key regulators for the functional contrast.

The flexibility provides vast advantages over conventional rigid electronics; flexible printed circuit (FPC) boards have become an industrial standard for consumer electronics and medical implants, 7– 10 where large area, extreme thinness, and compliance to curved surfaces are the key requirements for the functional passive and active elements.

Second, target genes of RB1, which is known to be negative regulator of the S-phase entry, showed positive correlation (i.e. upregulation in EKCs; EGUCHI_CELL_CYCLE_RB1_TARGETS, q-value FDR = 4.76 × 10−3) [ 30].>> Then we proceeded to find genes that are the key regulators for the functional contrast on PC2.

Although it may have started as something of a high-profile academic curiosity 10 years ago [ 3, 4], expression quantitative trait locus (eQTL) analysis has become a key tool for the functional understanding of the results of genome-wide association studies (GWASs) [ 5].

The biomimetic approach mimicking in vivo micro environment is the key for developing functional tissue engineered constructs.

Proper patient selection is the key for excellent functional outcome and high rate of survivorship of implant following UKR.