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The docking results were further verified developing a pharmacophore model which clarified the key features required for an optimal hPepT2 affinity and confirmed the main factors governing the hPepT2/hPepT1 selectivity.
The data demonstrated two key features required for a SDSL library with a predicting power: (i) spectral divergence distinctive lineshape for different elements; and (ii) spectral convergence similar lineshape for the same element in different contexts.
In this regard, a ligand-based pharmacophore model was developed highlighting the key features required for general antimicrobial activity.
A survey of existing virtual machine introspection tools is necessary to address various possible research gaps and to focus on key features required for wide application of virtual machine introspection techniques.
They were given a 1-day training in Bengali, (groups of 20 25) on finding children with impairments/epilepsy using previously tested flip books, and written information with visual illustrations, and a list of key features required for case finding.
The aim of this study was to conduct a pilot randomised controlled parallel arm trial, to establish key features required for the design and implementation of a large-scale trial on acupuncture for chronic neck pain.
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However, yeast has all the key features required to successfully apply forward genomic approaches.
Based on the literature survey, we identify common findings and key model features required for a sound assessment of future storage requirements.
Until now synthetic methods to AF analogues have been limited, this has restricted both understanding of the key structural features required for binding and also how this chemotype could be developed to an effective therapeutic agent.
In the present study, we have developed an atom-based 3D pharmacophore model using PHASE module, which provides the key structural features required for the biological activity.
In this pilot study, we have focused on establishing the key design features required for a full scale randomised controlled trial of the effectiveness of acupuncture for chronic neck pain, where acupuncture is provided as an adjunct to usual GP care.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com