Individuals with parental history of type 2 diabetes can exhibit deficits in insulin secretion long before the development of overt diabetes, and progressive loss of β-cell function is another key factor for the development of type 2 diabetes in this susceptible population (12, 15, 16).
Cerebral edema (CE) is the key factor for the development of secondary brain injuries after severe traumatic brain injury (TBI).
The production of stable redox active layers on electrode surfaces is a key factor for the development of practical electronic and electrochemical devices.
Taking on a psychological perspective, motivation to learn is a key factor for skill development and participation in (further) education (Boeren et al. 2010; Manninen 2005; Gorges 2015).
Wear assessment of critical components subjected to relative sliding is a key factor for the development of advanced materials and surface treatments in automotive industry.
Muscarinic receptor overexpression, as we described in SIDS, could be a key factor for the development of vagal overactivity.
Dysregulation of apoptosis or programmed cell death is emerging as a key factor for cancer development [14].
This paper is dedicated to B. Hasslacher who recently passed away and whose pioneering ideas were a key factor for the development of the present work.
Therefore, to identify CTL escape mutations that are restricted to spread like those classified as "positive associations" in this study, should be a key factor for the development of future vaccines [39].
