Sentence examples for key end point from inspiring English sources

Thus, these data also suggest that statins may cause cell death by autophagy as the key end point effect.

Hence, the concept of healthspan has emerged as a key end point for geriatric studies to translate experimental findings into realistic clinical interventions [ 120].

Although the demonstration of objective responses is not a key end point in phase I studies, clinical assessment of response to therapy in this study was of interest.

The fact that our detection system is able to identify hsp70 promoter induction at low doses ([ 5]; Figure 2 and Additional file: 1) is an advantage over traditional hepatocyte culture systems which rely upon viability as the key end point.

CTL represent a key end point in many protocols which currently employ irradiated DC as APC, both in vitro and in vivo (Gong et al, 1997; Celluzzi and Falo, 1998; Fields et al, 1998; Szmania et al, 2001).

Comparisons of the use of aclidinium bromide and tiotropium bromide for the treatment of chronic obstructive pulmonary disease often concentrate on key end points (exacerbations) at the expense of other benefits and risks.

For key end points, peak and total (area under curve) responses were compared among groups.

Key end points for screening include DNA damage (genotoxicity), cell cycle changes, endocrine disruption, and altered mammary gland development.

Key end points were QoL at 18 weeks, measured with EORTC Quality of Life Questionnaire (QLQ -C30 and QLQ -C30, and overall survival.

Pair-wise comparisons between FF/VI and placebo were performed for all secondary efficacy end points and other key end points using Repeated Measures Mixed Models for the ITT population.

To estimate these, a process of calibration was carried out, by allowing transition probabilities to vary within established ranges, so that modelled predictions of key end points for unvaccinated girls matched currently available epidemiological data in the presence of screening.