Ribonucleoproteins (RNPs) mediate key cellular functions such as gene expression and its regulation.
It is well known that the action of dFdC against cancer can affect endogenous RN and dRN pool sizes that play essential roles in a broad range of key cellular functions.
K-Ras functions as a critical node in the mitogen-activated protein kinase (MAPK) pathway that regulates key cellular functions including proliferation, differentiation, and apoptosis.
It is becoming increasingly apparent that the cAMP signaling pathway uses compartmentalization as a strategy for coordinating the large number of key cellular functions under its control.
Microtubule dynamics are important for a variety of key cellular functions such as intracellular trafficking, adjustment of the cell surface proteome, or adhesion structure turnover.
This protein facilitates favorable antitumor drug response through a variety of key cellular functions, including cell cycle arrest, senescence, and apoptosis.
Protein kinase C activation is integral to an abundance of intracellular signaling pathways; specific isozymes play roles in most key cellular functions, including survival vs apoptotic pathways, proliferative vs quiescent pathways, receptor desensitization, and cytoskeletal architecture, among many others.
Together, these observations suggest a participation of Nme genes in key cellular functions that have been conserved throughout evolution.
Since these specific genes appear to have key cellular functions and characterize tumor type and grade, future investigations as far as their potency as therapeutic targets are warranted.
miRNAs are emerging as important gene regulators and intensive research of their functions and targets have revealed a role of miRNAs in several key cellular functions.
Put together, our findings reveal a systematic loss of control by the host leukocytes over key cellular functions, including DNA synthesis, mitotic exit and self-repair response.
