In other words, even the remaining AhR still expressed in P20E cells is powerful enough to keep the expression of the ERE-target genes suppressed.
But when DNA damage accumulates as it does with age SIRT1 becomes too busy fixing broken DNA to keep the expression of hundreds of genes in check.
I wonder whether the French, being unable to insure an ironclad legal bastion against the practical effects of ethnic hatred, keep the expression of such hatred out of public discourse in an effort to banish it from the mainstream political arena.
And the real challenge we face is not how to resolve our differences — something that won't happen any time soon — but how to keep the expression of those differences within bounds.
Interestingly, I1-FFL architectures are the most abundant ones in bacteria and yeast [8], being reasonable that this abundance is a consequence of the specialization of the I-FFL to operate as time pulse generator and keep the expression of its target genes tightly suppressed in absence of external stimuli.
2582 4214 regions shows that HPV-16 exploits posttranscriptional mechanisms probably to keep the expression of the E6 and E7 proteins at a suitably low level.
This means that the intronic miRNA can keep the expression of its host gene in its homeostatic regime, while filtering out fluctuations, without exerting a strong reduction of its concentration.
In addition, they may keep the expression of stress response genes under tight control, to prevent the metabolic waste and self-inflicted damage that can be caused by a runaway stress response [ 13].
20 The paradox is explained by further studies; under given circumstances, Tregs may also produce IL-4, interferon (IFN -γ, or IFN -γ but keep the expressior of Foxp3.
On our Web page, these interactions are depicted in the following way: Lmx1b → En1, Lmx1b → En2 and Lmx1b →Wnt1, meaning that Lmx1b keeps the expression of En1, En2 and Wnt1, respectively, on overtime.
