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Under normal growth conditions, p53 is kept latent in various ways, e.g. by keeping it in the cytoplasm, by targeting it for proteasomal degradation, or by inhibiting binding to its DNA target sites [2].
It is likely that the elderly kept latent infection of M. tuberculosis for long years, and the age-associated decline in immune response caused development of active TB, while the younger patients developed active TB soon after initial infection (Tufariello et al. 2003).
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The activation of acute disease in immunocompromised patients and immunohistochemical data obtained on mice [ 59] suggest that under normal conditions both diseases are kept in latent form by the host immune system.
I try hard to keep any latent theological concerns out of my work.
In a normal person the immune system (the T lymphocytes, those that mature in the thymus, in particular) keeps the latent viruses in check.
At NIPH, no total counts of reported syphilis cases are kept, but late latent probably represent a majority (more than 50%).
This scheme is proposed as a direct analogy to the control mechanism of PrrC which is kept in its latent state via the interaction with the associated RM system.
IGF binding proteins keep this molecule latent.
The variances of the latent variables incorporating local dependence were also fixed, but the residual variances of latent exposure and the latent neurobehavioral functions were kept free.
Although DE data will ideally be kept under secure conditions to ensure confidentiality, the latent privacy risk of data storage cannot be dismissed.
The number of latent variables (or PLS components) to be kept was determined with cross-validation.
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CEO of Professional Science Editing for Scientists @ prosciediting.com