Sentence examples for keep the conformation from inspiring English sources

Here we tested the modification of the PNA backbone in order to keep the conformation most similar to the well established original aegPNAs.

The main effect of the mica substrate was to keep the subunit conformation in a straighter form compared to its equilibrium state in solution.

In the "context" of stabilized chromatin, regions of histone acetylation "islands" are used to keep the active conformation at specific positions.

For the MIR method, heavy atom derivatives, which keep the protein's conformation isomorphous, and crystals of the native protein are needed.

In simulation MD_A_3, the flanking bases kept the open conformation for 13 ns.

That is why in the acidic condition the ligand rimantadine can help Asp44 to keep the channel in the closed conformation.

We therefore propose that specific linear arrangements of regulatory elements are incompatible with long term replication of the epigenetic information necessary to keep the chromatin in an open conformation.

The negatively charged C terminus of CHMP proteins functions as an auto-inhibitory domain, interacting with the positively charged N terminus to keep the protein in a 'closed' conformation which masks the membrane binding properties of the N terminus (21– 21).

Activation of all PKC family members is controlled by a so-called pseudo-substrate (PS) domain in the NH2-terminus that resembles PKC substrates and forms an auto-inhibitory loop to keep the enzyme in an inactive conformation.

Phosphorylation allows for the binding of the kinase domain to pseudosubstrate (within their own regulatory domain) to keep the enzyme in a latent conformation or promotes PKC binding to real substrates for full activation.

In the absence of growth factors, AKT is inactive because intermolecular interactions between the pleckstrin homology (PH) and kinase domain (KD) keep the kinase in a closed conformation (Calleja et al., 2009).