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The interaction between the FA-modified nanoconjugates and KB cells was enhanced through overexpression of FA receptors on the surface of the KB cells.
Turek, J. J., Leamon, C. P. & Low, P. S. Endocytosis of folate-protein conjugates: ultrastructural localization in KB cells.
The ruthenium chlorin conjugate was found to accumulate preferentially in the endoplasmic reticulum of KB cells.
Cellular uptake of the nanogels (KB cells) was also monitored by confocal microscopy.
Cellular uptake of nGO by KB cells increased steadily with the increase in ligand density.
MLE showed a dose-dependent inhibition of cell proliferation of KB cells.
In addition, FPHP nanoparticles exhibited much greater cytotoxicity in KB cells than did FHP nanoparticles.
Cell uptake studies were carried out in KB cells (human nasopharyngeal epidermal carcinoma cell line).
A stronger interaction between the nanoconjugates and KB cells was observed in the presence of a magnet.
Furthermore, laser- and/or radio frequency-induced nanoconjugates in combination with external magnetic application reduced the viability of KB cells.
Despite a statistically significant in vivo photodynamic efficiency for Rut4, cellular localization in human oral carcinoma KB cells using fluorescence microscopy demonstrated that both conjugates Rut1 and Rut4 accumulated only in cytoplasm of KB cells but not in the nucleus.
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