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Eight applications referred to a systematic review in order to justify the duration of follow up during a trial (see Additional file 8).
Although this limitation is acknowledged, a double-blind design, as well as less flexibility in AED changes, could not be justified for the duration of follow-up required to demonstrate clinically meaningful long-term effects on HRQoL.
There was no significant difference between the two groups to justify the longer duration of therapy [ 32].
And the end justified the means.
The pharmacokinetic properties of azithromycin justify the short treatment duration of only one drop twice-daily for 3 days for a rapid antibacterial action 29.
Therefore; in order to guide the empiric antibiotic treatment it is important to evaluate cheap and inexpensive CRP assay as a rapid test to justify the use and duration of antibiotics treatment in many settings in developing countries.
As LBP is an episodic disease, it is not clear whether a sufficient number of patients with LBP will be LBP-free for at least one month ("non-episode") to justify the use of this duration in the definition of pain free episode.
Optimality models [ 17, 62] provided an explicit ordered prediction of the effect of our sex ratio manipulation on the duration of copulation, thus justifying the examination of statistical tests for ordered alternative hypotheses, i.e. ordered heterogeneity (OH -test [ 63] in additiOH -testnventional unordered statistics.
This duration probably does not justify the burden of an initial tunneled catheter in all patients with AKI receiving RRT.
Levosimendan seems to reduce catecholamine requirement, the need for mechanical circulatory support, and the duration of critical care, which can justify the cost of this drug.
According to BioFire, the device "is only authorized for the duration of the declaration that circumstances exist justifying the authorization of the emergency use".
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