Your English writing platform
Discover LudwigExact(22)
Despite it being renowned, this ligament probably offers little, if any, significant contribution to craniocervical junction stability.
While demonstrable on cadaveric dissection, both the identification of these smaller ligaments (or need to identify these ligaments) on clinical MRI assessment as well as the contribution of these structures to overall craniocervical junction stability is limited and, as such, injury to these ligaments in isolation is probably of low clinical significance.
However already at lower concentrations there were significant increases in permeability that could reflect paracellular leakage due to decreased tight junction stability.
It has recently been found in zebrafish that individual knockdown of genes implicated in junction stability such as Rap1b, Pak2a, β-Pix or ccm1/krit cause hemorrhagic phenotypes [43] [45].
In mature stable vessels, VECad is concentrated at endothelial cell-cell junctions and is essential for junction stability, whilst NCad is mainly localized across the cell surface.
We show that ICAM-2 regulates early junction stability and the transient accumulation of NCad at endothelial junctions in loosely established contacts.
Similar(38)
Further studies with an in vitro approach need to be conducted to elucidate whether the transcriptional activity of β-catenin Lef-1 and/or increased cell-junction stability is of importance in ovarian tumorigenesis.
Ligaments bind these two structural components of the craniocervical junction providing stability.
The association of different layers relies on E-cadherin based cellular junctions, whose stability can be affected by actin turnover.
miR-155 promotes EMT by targeting RhoA GTPase, which regulates cellular polarity and tight junction formation and stability [40].
Rac1 is key regulator of the actin cytoskeleton, cell motility, junction assembly and stability and can modulate assembly and disassembly of adherens junctions [ 28- 32].
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com