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The point mutation we made in the three-was junction is indicated with a purple box.
Arcs connect splice junctions identified by reads spanning the splice junction; the number of reads aligning to each splice junction is indicated.
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An exon junction with intronic sequence is indicated as "i" (for example, Ri6middle = shortened intron 6 of RNPEP)).
The importance of gap junction-associated cell communication is indicated by the association of mutations in Cx genes with a range of inherited human disorders (5– 7), mouse models (8) and expression and/or localization changes in various disease processes including cancer (9).
Autocellular junction in the ILso process is indicated by an arrow in (E ).
The junction between domain C and D is indicated by the letter C in a circle.
The junction between domain A and B is indicated by the letter A in a circle.
The junction between domain B and C is indicated by the letter B in a circle.
The junction where broken chromatid ends were joined is indicated by the red ×.
The trowal is indicated by a series of blue and red junction lines.
Many of the underlying mechanisms of chemotherapy-induced gut toxicity (CIGT) remain poorly understood, but tight junctions have been indicated to play a role in the pathogenesis of CIGT.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com