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Whether recombination in the DSBR pathway results in chromosomal crossover is determined by how the double Holliday junction is cut, or "resolved".
Chromosomal crossover will occur if one Holliday junction is cut on the crossing strand and the other Holliday junction is cut on the non-crossing strand (in Figure 4, along the horizontal purple arrowheads at one Holliday junction and along the vertical orange arrowheads at the other).
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I would hate my drive home even more if Radio 3's Late Junction was cut from the airwaves (Letters, 20 March).
Briefly, for each sacrificed mouse, 10 cm of the small intestine beginning at the gastroduodenal junction was cut, and the interior of the small intestine was flushed twice with a total of 2 mL of cold PBS.
Alternatively, if the two Holliday junctions are cut on the crossing strands (along the horizontal purple arrowheads at both Holliday junctions in Figure 4), then chromosomes without crossover will be produced.
During meiosis, Holliday junctions are cut by endonucleases to generate crossovers that are key to the proper segregation of chromosomes [ 4, 5].
Each bar represents one cell and the scale indicates the amount of bound Ds or Ft in arbitrary units at junctions between cells (note scale is cut off at 20 units), also see Figure 1 figure supplement 1. Sloped top edges represent the difference between proximal and distal cell edges within one cell.
The reconstruction is cut along the adherens junctions, and shows the entire face of the active zone.
Splice junctions are points on a DNA strand at which an intron is cut out in gene expression, right before the transcripts are translated into protein [ 10].
If the D-loop is cut, another swapping of strands forms a cross-shaped structure called a Holliday junction.
Except for the utero-tubal junction, which was cut in longitudinal direction, all segments were cut in transverse section.
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