In the NP WCEseq library, the peak was preceded by a steady upward trend upstream of the TSS followed by a gradual decline after the sharp jump downstream of TSS (Fig 4, middle left panel).
I've seen migrating salmon jumping up the weir downstream.
One possible explanation for this could be that strong activation of DNp09 neurons inhibits downstream targets involved in jumping behavior, such that when DNp09 activation stops, these neurons are released from inhibition showing rebound excitation, thereby triggering the observed jumps.
The products of two other identified genes, JTB (jumping translocation breakpoint) and NDRG1 (N-myc downstream regulated gene 1) are associated with UV resistance in 293FT cells and resistance to doxorubicin and retinoic acid in hepatocellular carcinoma cells.
Crystal-clear water runs over bleached stones, with plenty of opportunities for jumping off rocks and sliding down natural waterslides before floating downstream under the desert sun.
The fish bore downstream and jumped again and again, growing increasingly sloppy as it tired.
Application of the aforementioned MaSuRCA filtering procedures for jumping libraries was applied and yielded ∼4.5 million distinct mapped read pairs for downstream overlap layout consensus assembly.
"As an independent anything, you deal with a lot of insecurity; when you make documentaries, it's like going downstream on a river on an ice floe, never on solid ground, just jumping from one project to the next, hoping each time that the chunk of ice you land on is bigger than the last one".
Table B2 groups these by insert size and summarizes the outcome of the MaSuRCA jumping library filters on these as well as the estimated clone coverage presented to the downstream overlap assembler.
