First, the scenarios used to elicit judgements in this study may not have been sufficiently clear cut in terms of the conflict between principles.
Moreover, patients deemed to be too severely affected by the stroke or too severely ill to be positioned upright (clinical/nursing judgement) were not included in this study.
However, in this study, judgement criteria in favour of colloids were secondary in nature and the weakness of the benefit led the authors to consider their results as investigational only [15].
The impact of the recommendations on system effectiveness was qualitatively assessed, based on expert judgement of the partners involved in this study, for each of the above-mentioned areas.
In this study, judgement reliability R s was no different between paper case simulations and physical simulations, thus we can reject explanations focusing on participants' judgement consistency.
Sixty percent of respondents who had not had their eyes tested in the past two years said the main reason for not going was that they had not had a problem with their eyes, which is consistent with the difficulty with judgements about changing eyesight noted in this study.
In retrospect, therefore, the judgement call that this study used a valid behavioural outcome measure appears to have been erroneous, and the study should not have been included.
Additional discussion on other limitations of this study can be found in Additional File 1: Appendix 4. Compared to clinical judgement, the Naïve Bayes model developed in this study is able to guide rechallenge decisions more consistently and thus allows clinicians to make more confident decisions on whether to rechallenge a patient with the same drug after a prior serious ADR.
In this study, consumer judgements of products designed, parts procured from and assembled in both highly and newly industrializing countries were obtained.
The judgement of the onset of cerebral bleeding in this study was cautious, and the onset was probably in many cases even earlier than we report.
