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These studies reveal common genetic influences on withdrawal-associated anxiety, convulsions, and escalated drinking that may contribute to relapse, setting the stage for the identification of novel medications to jointly target these effects.
We strongly believe that identification of mediators of translation such as eIF4E may enable future design of therapeutic modalities that can jointly target several pro-malignancy factors at once.
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Education programmes jointly targeting pastoralist households and extension officers may offer a synergistic route for improving herd health in a rapidly changing environment.
Longini et al. [4] showed that in the case where interventions were used jointly (targeted antiviral prophylaxis, quarantine and pre-vaccination), the pandemic could be stopped at the source even for basic reproductive numbers as high as 2.4.
Moving forward, the iPrEx AWG has developed an integrated adherence counseling approach that jointly targets promoting PrEP use and other behavioral strategies to prevent HIV-infection.
For pairs of genes predicted to be jointly targeted by 10 or more TFs, we found a 4% and a 6% increase in absolute and positive correlations respectively, compared with random pairs of genes.
Particularly exciting are the new combinatorial approaches to target cancer stromal cells: combined antagonists of monocyte α4β1 integrin and SDFα or IL-1β inhibit tumour inflammation and growth [ 90], and a recombinant protein jointly targeting integrins and VEGF is an effective inhibitor of breast cancer angiogenesis [ 91].
The tracking procedure would be based on the jointly estimated target's position.
In this paper, we extract representative sentences through data-weighted reconstruction approach(DWR) by jointly leveraging target scientific paper's abstract and citation sentences' content and structure.
In the presence of unknown measurement noise variances, clutter and detection probability, improved RFS filters capable of jointly estimating target states, and unknown parameters were proposed (see e.g., [9, 15, 19] and references therein).
This points to the strength of our method in discovering complex interaction scenarios where multiple regulators may jointly regulate target genes with varying time-delays.
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