Primates, in contrast, jointly sample color and luminance information through the same set of photoreceptors [6], [70], [71].
Our study was done jointly (sampling sites and seasons) with the previously mentioned study.
Negative eigenvalues were not obtained in our simulations and indeed seem infeasible, because the relationships were jointly sampled.
However, it would be possible to jointly sample from sequence data and serological data using these methods.
When a MH algorithm is used to jointly sample the marker effect and the locus-specific variance, the BayesB method is computationally intensive.
Nevertheless, Meuwissen et al. [ 4] used a Metropolis–Hastings (MH) algorithm to jointly sample the marker effect and the locus-specific variance because they argued that "the Gibbs sampler will not move through the entire sampling space" for BayesB.
As previously noted, the posterior correlation between v and s can be high; hence, it might be advantageous to jointly sample these two parameters with a bivariate random walk MH sampler, as demonstrated with a different application by Ntzoufras [ 13].
Other recent methods do not fix the number of shifts or their locations on the phylogeny, but instead implement algorithms that estimate them (e.g. reversible-jump), while jointly sampling OU parameters [ 56].
Usually in the BayesB method, a Metropolis–Hastings (MH) algorithm is used to jointly sample the marker effect and the locus-specific variance, which may make BayesB computationally intensive.
Accounting for unertainty in σ As mentioned (Sec 2.4), to account for the fact that the noise standard deviation is only approximately known, one can jointly sample values of σ and the error terms ε i, j (i = 1, 2, j = 1, …, K) at each interation in STARCIST (for a given patient).
