Sentence examples for joint specificity from inspiring English sources

However, the relative joint specificity arising from immunity toward an antigen whose expression is not joint restricted is puzzling.

However, the Gdf5 promoter can be very useful when chondrocyte specificity is not required but joint specificity is.

Our data showed that OA genetic susceptibility did exhibit joint specificity and that this susceptibility had a greater role in female disease.

A joint specificity value of 0.90 at the 1.75 cut-off score, 0.89 at the 1.67 cut-off score and 0.73 using the Bolton algorithm was achieved.

Altogether, these data agree with the hypothesis that OC(D) joint specificity is due to the interaction of different molecular mechanisms, which are altered in all joints (systemic defect) but trigger a different susceptibility (joint specificity due to the different biomechanical constraints sustained by the joints).

Joint specificity is explained by the deposition of the GPI onto the articular cartilage surface, binding of anti-GPI antibodies to the surface and subsequent complement-mediated inflammation [ 22].

For example, the method could conveniently calculate the joint sensitivities and joint specificities and make corresponding statistical inferences, such as 95% credible intervals (Table  3).

In the framework of frequency statistics, such as capture recapture approaches or constrained maximum likelihood estimations, it is often difficult to obtain statistical inferences about the joint sensitivities and joint specificities in these types of studies.

At present, however, we can not exclude that some of the CD4+CD28null T cells with access to the joint have specificity for cartilage-derived and/or citrullinated candidate antigens.

Measurement of complexes between complement-activation products and joint-specific molecules might provide improved specificity to the diagnostics of RA and may give better distinction between patients with complement-mediated joint inflammation and healthy individuals.

For absence of tender joints, the specificity and PPV were 96.1% and 91.7%, respectively.