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Patients undergoing prosthetic hip joint revisions were recruited from those attending the Department of Orthopaedic Surgery at the Southern General Hospital, Glasgow.
Surgical intervention on distal extremities in horses is a standard of care for many orthopaedic conditions including splint bone fractures, condylar fractures, arthroscopic joint revisions, and various other conditions [ 1- 3].
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The resulting adverse reaction to metal debris (ARMD) frequently leads to early joint revision.
The few available studies directly comparing aseptic and septic joint revision surgery report conflicting results.
Use of antibiotic-loaded bone cement for prophylaxis against infection in the second stage of a two-stage total joint revision involves low doses of antibiotics.
Use of commercially available antibiotic-loaded bone-cement products has been cleared by the United States Food and Drug Administration only for use in the second stage of a two-stage total joint revision following removal of the original prosthesis and elimination of active periprosthetic infection.
In cases of discordance, a joint revision of all the material took place in the presence of an independent referee who made the final decision after discussion.
We retrospectively reviewed 219 consecutive joint revision replacements between May 2004 and February 2013.
Specimens of soft tissue and bone were collected from regions of bone resorption during joint revision surgery.
In case of discrepancy, joint revision of the ambiguous samples was performed to assure the consistency of definitive results.
Studies were included if they reported THR-related deep SSI or infection requiring a joint revision procedure as an outcome.
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