Our range of CM values for MOR 555 partially overlap that of Hutchinson et al. [7], with our more caudally distributed range (0.295 0.652 m cranial of the hip joint) explained by our smaller thoracic volume (see above).
In this simplified clinically interpretable model, the moment equilibrium around the centre of rotation of the ankle joint explains this mechanism as the multiplication of the force with its moment arm determines the share in loading.
Constitutive explanations, in contrast, explain a phenomenon by describing the mechanism that underlies it, as when one says brain regions, muscles, and joints explain reaching.
This might also be of putative clinical importance, since such compensational movements which outrange the normal functional working parameters of the joint might explain symptoms in neighboring and/or contralateral joints, which are commonly described in both human and animal models (secondary hyperalgesia).
39 The authors proposed that the distribution of muscle spindles around each joint could explain differences in perception of position sense and commented on the relative importance of proximal joints in localizing the endpoint.
In addition, trauma to a cutaneous branch originating from the common peroneal nerve 11 mm above the joint may explain anecdotal cases of previously unexplained local dysesthesia on the lateral side of the knee [8].
Additionally, some claim that ongoing inflammatory processes in the thoracic joints may explain limitations of chest excursions, by causing pain and stiffness, and thus contributing to reduced pulmonary function [ 5, 9, 11].
This single joint analysis explains why even very subtle changes in individual joints, assigned by one reader, translates into measurable changes at the level of change in total Sharp score and differentiation between treatment arms.
A local taco joint, Poliquin explained, gives away free food if that hitter strikes out.
"Hundreds of thousands of people of Uyghur and Kazakh descent are being held indefinitely in extra-judicial internment camps in Xinjiang today," the joint statement explains.
