> In the great majority of joint examined, a high degree of intra-articular PD signal may be found at the level of synovial proliferation (Fig. 1g, h).
In most ethnic groups OA is extremely common, with its prevalence and incidence varying depending on the diagnostic criteria used and on the joint examined, with disease of the hands and of the knees being particularly prevalent (Ref. 4).
The joints examined were butt welded and longitudinally welded.
Both the experimental compliance method and the virtual crack closure technique proved applicable for the interpretation of the fracture mechanics data of the structural joints examined, provided that stiffness degradation can be accurately described.
There was excess clear joint fluid in the carpal joints examined.
Of the 848 joints examined, 74 displayed synovitis, and 66 (89 %) of these had OCD.
The total number of affected joints was calculated based on the presence of either tenderness or swelling in each of the joints examined.
The results for joints examined at all time points were pooled since no time effects were evident for col II, col I and YKL40.
Also the definition of erosive disease differed between the studies, but the outcome used in the current study was the presence of any erosion in the joints examined.
*Tg197 mice injected (intraperitoneally) with the test peptide P-NT.II were killed at weekly intervals (N = 4 per group) for 4 weeks and their ankle joints examined.
