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While the choice of the SF-12 related to the fact that the KORA-survey was not specifically designed to study menopausal issues, using a generic instrument may also have advantages in a study which scrutinizes different conditions (obesity, diabetes, and depressed mood) as joint determinants of postmenopausal HRQL.
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Fibroblast-like synoviocytes (FLS) are recognized as a prominent joint-specific determinant of RA because of their hyperproliferative properties and hyperproduction of both proinflammatory cytokines that perpetuate inflammation and matrix metalloproteinases (MMPs) that contribute to cartilage destruction [ 3, 4].
The multivariate logistic regression model with Enter method was used to assess the joint effect of determinants related to perceived low numbers of patients.
We focus on the analysis of joint and disjoint genetic determinants across diseases.
In addition, we aimed to investigate whether EBV positivity is modified by the joint effect of these determinants.
Estimating the magnitude of the independent as well as joint association between these determinants and caesarean births is essential for designing interventions that promote healthy pregnancy outcomes.
While hip and knee OA both increase with age [14], evidence suggests that OA at these two joint sites has different determinants [15].
Although vastus medialis and lateralis are important determinants of patellofemoral joint function, their relationship with patellofemoral joint structure is unknown.
We conclude that besides polyarticular-muscle induced synergies and inertial coupling, articular conformity of the shoulder joint constitutes an additional determinant of inter-joint coordination stability that, to date, has been neglected.
Our data suggests that the absolute level of IL-17 is not the only determinant of joint inflammation.
In a previous study self-reported joint hypermobility was a determinant of back pain persistent after childbirth [ 24].
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