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Additionally, the joint alignment of the shot-gun sequences to the human-mouse alignment offers the investigator a rapid way to defining specific regions for analysis and resequencing.
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Of note is the impact of joint alignment on the development of degenerative changes.
Although the femur was not considered in this work, the joint alignment outcomes of KA TKA have been reported previously (Dossett et al. 2014; Ji et al. 2016).
Overall, the above findings highlight the importance of joint alignment in the structural adaptation of Sb to loading and progression of OA [ 44] and suggest a mechanism whereby ligament changes precede cartilage pathology in the DH model [ 45].
It is difficult to obtain more specific quantitative measurements for comparison between different groups because of the inconsistency of joint alignment and measurement position.
The postoperative contact pressure profile showed overcorrection of the joint alignment, resulting in medial concentration of the peak contact pressure.
The most time-consuming procedure was the mechanical axis of the stifle joint alignment with the mechanical axis of the testing device.
However, although an examination was performed, there was no precise measurement of joint alignment.
The evaluation of joint alignment, fracture healing and reduction, arthritis grading according to Knirk and Jupiter and the degree of displacement was made on post-operative radiographs.
In addition, a study of 300 community-based individuals with knee OA [ 39] examined the relationship between obesity and knee OA and found that joint alignment mediated the effect of obesity on knee OA.
Although early postoperative radiographs showed partial loss of AC joint alignment in 3 patients (15%%) from group A and in 6 (30%%) from group B, poor satisfaction was only reported by 4 group B patients (20%%).
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